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by Dr. Joseph Mercola
January 09, 2024
from
Mercola Website
Story at-a-glance
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The
latest SARS-CoV-2 variant, JN.1, was first detected in
the U.S. in September 2023. By mid-December, it
accounted for about half of all COVID cases in the
country
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According to the U.S. Centers for Disease Control and
Prevention, the rapid spread of JN.1 suggests it may be
more transmissible and/or has greater immune-evading
abilities
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A
vaccinology concept called "immune refocusing" explains
how more dangerous viruses can be created by leaky
vaccines that do not prevent infection
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By
continuing with boosters, we accelerate immune escape.
Over time, variants will get better and better at
evading our immune responses, and those who keep taking
boosters will be the most vulnerable to infection of all
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Because of the mutations seen in JN.1, vaccinologist
Geert Vanden Bossche, Ph.D., predicts we will "very
soon" see variants that are more virulent but less
infectious. If this happens, healthy unjabbed
individuals are unlikely to be affected because their
first line of defense - their innate immune system -
still works as it should. The jabbed, on the other hand,
whose innate immune systems have not been trained, and
whose adaptive immune systems have become increasingly
useless, will be at very high risk of severe
complications and death
The latest SARS-CoV-2 variant, JN.1, was first detected in the U.S.
in September 2023.
By mid-December, it accounted for about half of
all COVID cases in the country, 1 and calls to get the latest
"updated" COVID shot resumed.
Cases associated with this variant are also on
the rise in,
According to the U.S. Centers for Disease Control and Prevention
(CDC),
the rapid spread of JN.1 suggests it may be more transmissible
and/or has greater immune-evading abilities: 3
"JN.1 is similar to BA.2.86 but has an
additional mutation (L455S) in the spike protein.
JN.1 continues to cause an increasing share
of infections and is now the most widely circulating variant in
the United States.
For the two weeks ending on December 23, 2023, JN.1 is expected
to account for 39-50% of all SARS-CoV-2 variants. That's an
increase from the projected prevalence two weeks ago of 15-29%.
We're also seeing an increasing share of infections caused by
JN.1 in travelers, wastewater, and most regions around the
globe.
JN.1's continued growth suggests that the
variant is either more transmissible or better at evading our
immune systems than other circulating variants."
JN.1 Is Not Associated With More
Severe Disease
The CDC does, however, stress that,
JN.1 does not appear to cause
more severe disease than any of the other variants we've seen in the
last couple of years, most of which have caused nothing more than
common cold symptoms...
The New York Times even noted: 4
"As far as experts can tell, JN.1 does not
seem to be causing severe illness in most other people, though
even a mild case can still make you feel 'quite miserable for
three or four days,' Dr. (William) Schaffner (infectious disease
specialist at Vanderbilt University Medical Center) said.
The symptoms of a JN.1 infection are similar
to those caused by previous COVID variants, including a cough,
fever, body aches and fatigue...
JN.1 will most likely remain the dominant
version of the coronavirus through spring, Dr. Schaffner said."
According to data from the British Office for
National Statistics, the most commonly reported symptoms among
COVID-19 patients in December 2023 included: 5,6
Of these, the only symptoms that can be
considered "novel" are problems sleeping and worry/anxiety, which
could easily be the natural outgrowth of having spent the last four
years bombarded with fear-based propaganda about
COVID...
Mass Vaccinating During Active
Pandemic Is a Disaster
Despite three years of evidence to the contrary, the CDC still
insists that existing vaccines are the best way to protect yourself
against JN.1.
In the video
far below, vaccinologist Geert Vanden
Bossche, Ph.D., discusses the challenges of controlling transmission
with vaccines, as even with mRNA technology we're still chasing the
virus.
His resume includes work with,
As some of you may recall, in 2021, Vanden
Bossche 7 published an open letter 8 to the World Health
Organization (WHO) in which he warned that,
implementing a global mass
vaccination campaign during the height of the pandemic could create
an "uncontrollable monster" where evolutionary pressure will force
the emergence of new and potentially more dangerous mutations.
"There can be no doubt that continued mass
vaccination campaigns will enable new, more infectious viral
variants to become increasingly dominant and ultimately result
in a dramatic incline in new cases despite enhanced vaccine
coverage rates.
There can be no doubt either that this
situation will soon lead to complete resistance of circulating
variants to the current vaccines," Vanden Bossche wrote.
9
His warning fell on deaf ears, but evidence
clearly shows that he was on the right track.
Increasingly, variants
have mutated to evade both natural and injection-based immunity,
with those having received
the COVID shots,
now being at higher risk
of infection than their unjabbed peers...
The COVID Jabs Are Driving
Potentially Hazardous Mutations
As explained by Vanden Bossche,
the COVID jabs, from the beginning,
have produced the wrong immune response, which inevitably leads to
immune escape.
In summary,
when you vaccinate against one variant, in
this case the original Wuhan strain, your immune system will
produce antibodies against that strain.
When your immune system is then hit with a
second variant - as is the case when the vaccine is a step
behind - it will be overly focused on the original strain, which
allows the second strain to pass through its defenses.
Vanden Bossche's concern now is the possibility
of variants capable of causing more severe symptoms.
We haven't seen that yet, but as he notes in this
interview, the mutations are no longer limited to conserved domains
shared by many variants, but are also found in other viral proteins,
some of which may enhance infection.
He goes on to explain a vaccinology concept called "immune
refocusing," which is how more dangerous viruses can be created.
Immune refocusing happens when you have a vaccine breakthrough
infection, meaning the vaccine did not result in enough neutralizing
antibodies to block the virus.
This is also known as a "leaky vaccine"...
The breakthrough infection boosts production of previously induced
antibodies, giving you very high titers.
And, while they have very
low neutralizing capacity, the sheer number of them can still have
some neutralizing, albeit short-lived, effect on the virus.
During the time the antibodies have this neutralizing effect, they
bind to the dominant epitopes (an epitope is the part of the antigen
that is recognized by your immune system), and by doing so, the
subdominant epitopes that normally are outcompeted by the dominant
ones can now be recognized by your immune system.
By continuing with boosters,
we accelerate immune escape...!
Over time, variants will get better and better
at
evading our immune responses,
and those who keep taking boosters
will be the most vulnerable to infection of all...
The problem is that once these antibodies begin to lose their
neutralizing capacity, they become sub-neutralizing, which allows
for the propagation of more infectious variants.
The mRNA jabs make immune refocusing all the more
likely because they induce antibodies with low affinity to the
immunodominant epitopes from the start, and automatically prioritize
subdominant epitopes.
This, Vanden Bossche explains, is why:
"... after the second dose of mRNA vaccine,
we have seen cross-neutralizing antibodies against several
different variants.
Of course the manufacturers and the WHO were
saying,
'Oh wow, this is great... We are now
broadening the immune response.'
(But) they have not taken into account that
they (are) generating low-affinity antibodies and that is why
they... very rapidly evolve toward sub-neutralization,
suboptimal titers that... drive immune escape."
The key take-home from all of this is that our
immune response will never get any better if we continue this way.
In fact,
by continuing with boosters, all we're
doing is accelerating immune escape, Vanden Bossche warns...
Over
time, the variants will get better and better at evading our immune
responses, and those who keep taking boosters will be the most
vulnerable to infection of all.
This is the exact opposite of what vaccination is all about, and
could result in an absolute public health disaster, especially
should variants also begin to mutate into strains that cause more
serious symptoms.
What Concerns Vanden Bossche about
JN.1
While JN.1 does not appear to be any more troublesome than previous
variants, Vanden Bossche worries about what this particular variant
tells us about the immune pressures that gave rise to it in the
first place.
The neutralizing domains of
the spike protein have completely
changed from the original.
They're even completely different from BA.2,
from which JN.1 arose, as shown in a November 2023 study in the
journal Vaccine. 10
The problem, Vanden Bossche explains, is that,
while vaccine developers point to high titers
of neutralizing antibodies against various variants (including
JN.1) at two weeks post-jab, they're ignoring (or hiding) the
fact that these are not true neutralizing antibodies.
Vanden Bossche refers to them as
pseudo-neutralizing, because:
"... they have no specificity for the
monovalent epitope.
They can only interact with the multimeric
presentation of the spike on a viral particle, or on viral
aggregates, and therefore their neutralizing effect is very much
limited in time, and that is... what JN.1 tells us.
JN.1 is fine in its own right, but it tells us something which
is extremely worrisome.
It tells us, basically, that the highly
vaccinated populations have... progressed their antibodies to
stabilizing aggregates that are now primarily taken up by
antigen-presenting cells and are driving mitigation of
infection, because even vaccinees (vaccine recipients) who are
regularly exposed have no severe symptoms...
The vast majority of regularly exposed have, still, relatively
mild symptoms, so mitigation of the disease is now explained by
the cytotoxic T cells that will abrogate infection, or kill
cells that have been infected...
That is another way of mitigating the
infection, which is driving... more infectious variants like
JN.1...
We see that JN.1 spreads like wildfire. It has outpaced all of
the co-circulating variants globally in no time... Secondarily,
we see a very clear surge in cases of hospitalization, severe
disease and death... in several European countries...
But the most interesting thing, when you look at the changes in
JN.1... there is something extremely spectacular.
For the first time, the mutations are no
longer limited to conserved domains... those that are shared
among several different variants.
The mutations seen in JN.1... are very
uncommon.
We are also seeing a number of mutations that aren't even spike
specific anymore. They are located in other viral proteins, and
these mutations have an infection-enhancing effect...
They are, for example,
promoting the efficiency of viral protein
synthesis, or they are promoting the efficacy of
intracellular viral replication...
What I see is that JN.1 is the result of immune pressure on the
virus.
An immune pressure that... moved away very
clearly from targeting common epitopes that are shared among
several different variants... and it moved away from targeting
epitopes that are within the spike...
When you put all these things together, you can now clearly
confirm that... we have been shifting the immune focusing from
the humoral response to a cellular response...
This immune refocusing is driven by
antibodies of lower and lower affinity...
What this means is...
none of the updated vaccines will
work...!
Remember, every single time you have vaccine
breakthrough infection, you boost (the pseudo-neutralizing
antibodies), but... if this boosting effect no longer takes
place, or is diminishing... then you will see a decline in those
antibodies...
When the concentration diminishes... infection-enhancing
antibodies are a disaster, because these infection-enhancing
antibodies are also responsible for inhibiting the virulence of
the virus...
So now you are going to put suboptimal immune
pressure on viral virulence, and that is what's going on."
The Jabbed Will Be at Grave Risk
if SARS-CoV-2 Becomes More Virulent
Because of the mutations seen in JN.1, Vanden Bossche predicts,
we
will "very soon" see variants that are more virulent, meaning more
damaging and deadly.
If this happens, healthy unjabbed individuals are
unlikely to be affected, according to Vanden Bossche, because their
first line of defense - their innate immune system - still works as
it should.
As a virus becomes more virulent, it typically has to pay a fitness
cost, so it becomes less infectious.
In other words,
it won't spread
as easily, but when it does infect someone, it causes more severe
disease.
Vanden Bossche predicts that,
since the innate immune systems of the unjabbed have been continuously trained on all these different
variants, they are therefore less likely to become infected, and if
they do, they will be largely asymptomatic.
The jabbed, on the other hand, whose innate immune systems have not
been trained, and whose adaptive immune systems have become
increasingly useless thanks to the processes described by Vanden
Bossche,
will be at very high risk of severe complications and
death...
mRNA Jab Causes Off-Target Effects
The latest COVID injections contain a single modified RNA said to
correspond to the Omicron variant XBB.1.5., which was the dominant
variant in the U.S. for most of 2023, but which has since been
replaced by JN.1 and several other variants.
The SARS-CoV-2 virus mutates so quickly, there's simply no way to
keep up, let alone get ahead of it, and as explained above, this
catch-up game is ultimately what puts pressure on the virus to
mutate, and potentially into a more virulent form.
On top of that,
we now also know that the shots are producing
off-target proteins in 25% to 30% of recipients, and are
contaminated with DNA, both of which have huge potential to cause
harm...
Until or unless they fix those problems, the
risks are simply unacceptable, in my opinion.
But even if these issues were successfully fixed, we're still facing
a situation in which continued boosting will accelerate mutations
that could eventually make the virus deadlier again, at least for
those who have taken the shots.
It's basically a death spiral, and the only way to end it is,
to stop
taking boosters...!
There are no indications that our health
authorities will protect the public by withdrawing the
COVID shots,
so it's incumbent on each individual person to simply say no...!
Got the Jab? Take Action to
Safeguard Your Health
If you already got one or more jabs and now have concerns about your
health, what can you do?
First and foremost, never take another COVID
booster, another mRNA gene therapy shot or regular vaccine.
You
need to end the assault on your system.
If you developed symptoms you didn't have before
your shot, I would encourage you to seek out expert help.
At present, the Front Line COVID-19 Critical Care
Alliance (FLCCC) seems to have one of the best treatment protocols
for post-jab injuries.
It's called
I-RECOVER and can be downloaded
from covid19criticalcare.com. 11
Dr. Pierre Kory, who cofounded the FLCCC, has transitioned to
treating the vaccine injured more or less exclusively. For more
information, see
DrPierreKory.com.
Dr. Peter McCullough is also investigating
post-jab treatments, which you can find on
PeterMcCulloughMD.com.
The World Health Council (WHO) has also published lists of
remedies that can help inhibit, neutralize and eliminate spike
protein, which most experts agree is the primary culprit.
I covered
these in my 2021 article, "World Council for Health Reveals Spike
Protein Detox."
Video
Geert's Concern about
the New Covid Variant (JN.1)
Sources and References
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